The long-term impact of early treatment of multiple sclerosis on the risk of disability pension.

ABSTRACT:

Objective

The objective of this retrospective, observational study was to estimate the long-term impact of early treatment of multiple sclerosis (MS) on the risk of disability pension.

Methods

Our cohort comprised patients with MS in Sweden, identified in a nationwide disease-specific register (the Swedish Multiple Sclerosis Registry), who started treatment with a disease-modifying drug (DMD) between January 1, 2002, and December 31, 2012. We analyzed the association between time from onset of MS to treatment initiation and full-time disability pension using survival analysis.

Results

Our sample comprised 2477 patients. Unadjusted Kaplan-Meier failure functions showed that patients who started treatment within six months after onset had a lower risk of disability pens

SUBMITTER: Landfeldt E 

PROVIDER: S-EPMC5834562 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature