Phylogenomic Based Comparative Studies on Indian and American Commensal Staphylococcus epidermidis Isolates.

ABSTRACT: Staphylococcus epidermidis is a prominent commensal member of human skin microbiome and an emerging nosocomial pathogen, making it a good model organism to provide genomic insights, correlating its transition between commensalism and pathogenicity. While there are numerous studies to understand differences in commensal and pathogenic isolates, systematic efforts to understand variation and evolutionary pattern in multiple strains isolated from healthy individuals are lacking. In the present study, using whole genome sequencing and analysis, we report presence of diverse lineages of S. epidermidis isolates in healthy individuals from two geographically diverse locations of India and North America. Further, there is distinct pattern in the distribution of candidate gene(s) for

SUBMITTER: Sharma S 

PROVIDER: S-EPMC5835047 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature