Panax notoginseng Root Cell Death Caused by the Autotoxic Ginsenoside Rg₁ Is Due to Over-Accumulation of ROS, as Revealed by Transcriptomic and Cellular Approaches.

ABSTRACT: Panax notoginseng is a highly valuable medicinal herb, but its culture is strongly hindered by replant failure, mainly due to autotoxicity. Deciphering the response mechanisms of plants to autotoxins is critical for overcoming the observed autotoxicity. Here, we elucidated the response of P. notoginseng to the autotoxic ginsenoside Rg₁ via transcriptomic and cellular approaches. Cellular analyses demonstrated that Rg₁ inhibited root growth by disrupting the cell membrane and wall. Transcriptomic analyses confirmed that genes related to the cell membrane, cell wall decomposition and reactive oxygen species (ROS) metabolism were up-regulated by Rg₁ stress. Further cellular analyses revealed that Rg₁ induced ROS ([Formula: see text] an

SUBMITTER: Yang M 

PROVIDER: S-EPMC5836058 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature