Parathyroid Hormone Assays following Total Thyroidectomy: Is There a Predictive Value?

ABSTRACT:

Objectives

Parathyroid hormone (PTH) is a risk marker for hypoparathyroidism (hypoPTH). This study aimed to determine the predictive values of early PTH assays carried out at the moment of skin closure (PTH SC), to establish a treatment algorithm, identifying two threshold values. We assessed the reproducibility of this approach with two different immunoassay kits (hypoPTH) after total thyroidectomy, but its practical application is not consensual.

Study design

We conducted a prospective descriptive study, including all patients who underwent a total thyroidectomy between March 2012 and November 2013. Postoperative PTH SC levels, corrected calcium on postoperative days, and occurrence of hypoPTH symptoms were collected.

Results

Of 257 patients, the rate of hypoPTH was

SUBMITTER: Galy-Bernadoy C 

PROVIDER: S-EPMC5836170 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature