Clinical phenotypes of perinatal depression and time of symptom onset: analysis of data from an international consortium.

ABSTRACT:

Background

The perinatal period is a time of high risk for onset of depressive disorders and is associated with substantial morbidity and mortality, including maternal suicide. Perinatal depression comprises a heterogeneous group of clinical subtypes, and further refinement is needed to improve treatment outcomes. We sought to empirically identify and describe clinically relevant phenotypic subtypes of perinatal depression, and further characterise subtypes by time of symptom onset within pregnancy and three post-partum periods.

Methods

Data were assembled from a subset of seven of 19 international sites in the Postpartum Depression: Action Towards Causes and Treatment (PACT) Consortium. In this analysis, the cohort was restricted to women aged 19-40 years with information a

SUBMITTER: Putnam KT 

PROVIDER: S-EPMC5836292 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature