Cost-effectiveness Analyses of Antihypertensive Medicines: A Systematic Review.

ABSTRACT:

Context

Hypertension affects one third of the U.S. adult population. Although cost-effectiveness analyses of antihypertensive medicines have been published, a comprehensive systematic review across medicine classes is not available.

Evidence acquisition

PubMed, Embase, Cochrane Library, and Health Technology Assessment were searched to identify original cost-effectiveness analyses published from 1990 through August 2016. Results were summarized by medicine class: angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs), calcium channel blockers (CCBs), thiazide-type diuretics, β-blockers, and others. Incremental cost-effectiveness ratios (ICERs) were adjusted to 2015 U.S. dollars.

Evidence synthesis

Among 76 studies reviewed, 14 compared

SUBMITTER: Park C 

PROVIDER: S-EPMC5836308 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature