BRCA-Pathway: a structural integration and visualization system of TCGA breast cancer data on KEGG pathways.

ABSTRACT: BACKGROUND:Bioinformatics research for finding biological mechanisms can be done by analysis of transcriptome data with pathway based interpretation. Therefore, researchers have tried to develop tools to analyze transcriptome data with pathway based interpretation. Over the years, the amount of omics data has become huge, e.g., TCGA, and the data types to be analyzed have come in many varieties, including mutations, copy number variations, and transcriptome. We also need to consider a complex relationship with regulators of genes, particularly Transcription Factors(TF). However, there has not been a system for pathway based exploration and analysis of TCGA multi-omics data. In this reason, We have developed a web based system BRCA-Pathway to fulfill the need for pathway based analysis of T

SUBMITTER: Kim I 

PROVIDER: S-EPMC5836821 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature