Radical versus partial nephrectomy, chronic kidney disease progression and mortality in US veterans.

ABSTRACT:

Background

Partial nephrectomy is considered the preferred care for localized kidney tumors and may yield better patient and kidney survival and similar oncological outcomes compared with radical nephrectomy. We sought to reexamine these hypotheses in a large nationally representative cohort of US veterans who underwent radical or partial nephrectomy.

Methods

We identified 7073 US veterans who had a partial or radical nephrectomy between 2004 and 2013. We collected data on estimated glomerular filtration rate (eGFR) prior to admission for nephrectomy surgery, immediately after surgery and 180 days postsurgery. We evaluated the association of nephrectomy type and eGFR at different time points with long-term mortality risk in adjusted survival models.

Results

Patients w

SUBMITTER: Streja E 

PROVIDER: S-EPMC5837388 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature