Software Application Profile: PHESANT: a tool for performing automated phenome scans in UK Biobank.

ABSTRACT:

Motivation

Epidemiological cohorts typically contain a diverse set of phenotypes such that automation of phenome scans is non-trivial, because they require highly heterogeneous models. For this reason, phenome scans have to date tended to use a smaller homogeneous set of phenotypes that can be analysed in a consistent fashion. We present PHESANT (PHEnome Scan ANalysis Tool), a software package for performing comprehensive phenome scans in UK Biobank.

General features

PHESANT tests the association of a specified trait with all continuous, integer and categorical variables in UK Biobank, or a specified subset. PHESANT uses a novel rule-based algorithm to determine how to appropriately test each trait, then performs the analyses and produces plots and summary tables.

Impleme

SUBMITTER: Millard LAC 

PROVIDER: S-EPMC5837456 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature