Overall and abdominal obesity and incident aortic valve stenosis: two prospective cohort studies.

ABSTRACT:

Aims

The aim of this study was to examine the association of overall and abdominal obesity with aortic valve stenosis (AVS) incidence in two prospective cohorts.

Methods and results

We used data from the Cohort of Swedish Men and the Swedish Mammography Cohort, involving 71 817 men and women who were free of cardiovascular disease and had reported their anthropometric measures in 1997. Aortic valve stenosis cases were ascertained through linkage with nationwide registers on hospitalization and causes of death. Data were analysed using Cox proportional hazards regression. During a mean follow-up of 15.3 years, 1297 incident AVS cases (771 in men; 526 in women) were ascertained. Both overall and abdominal obesity, measured as body mass index (BMI) and waist circumference, resp

SUBMITTER: Larsson SC 

PROVIDER: S-EPMC5837465 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature