Body weight in adolescence and long-term risk of early heart failure in adulthood among men in Sweden.

ABSTRACT:

Aims

To study the relation between body mass index (BMI) in young men and risk of early hospitalization with heart failure.

Methods and results

In a prospective cohort study, men from the Swedish Conscript Registry investigated 1968-2005 (n = 1 610 437; mean age, 18.6 years were followed 5-42 years (median, 23.0 years; interquartile range, 15.0-32.0), 5492 first hospitalizations for heart failure occurred (mean age at diagnosis, 46.6 (SD 8.0) years). Compared with men with a body mass index (BMI) of 18.5-20.0 kg/m2, men with a BMI 20.0-22.5 kg/m2 had an hazard ratio (HR) of 1.22 (95% CI, 1.10-1.35), after adjustment for age, year of conscription, comorbidities at baseline, parental education, blood pressure, IQ, muscle strength, and fitness. The risk rose incrementally with

SUBMITTER: Rosengren A 

PROVIDER: S-EPMC5837553 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature