Influenza vaccination and risk of hospitalization in patients with heart failure: a self-controlled case series study.

ABSTRACT:

Aims

Evidence supporting yearly influenza vaccination in patients with chronic heart failure (HF) is limited, consequently leading to inconsistent guideline recommendations. We aimed to investigate the impact of influenza vaccination on the risk of hospitalization in HF patients.

Methods and results

We used linked primary and secondary health records in England between 1990 and 2013. Using a self-controlled case series design with conditional Poisson regression, we estimated the incidence rate ratio (IRR, 95% CI) of the number of hospitalizations in a year following vaccination with an adjacent vaccination-free year in the same individuals. We found the uptake of vaccination to be varied and generally low (49% in 2013). Among 59,202 HF patients, influenza vaccination was ass

SUBMITTER: Mohseni H 

PROVIDER: S-EPMC5837634 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature