Predicting progression from normal cognition to mild cognitive impairment for individuals at 5 years.

ABSTRACT: Recent evidence indicates that measures from cerebrospinal fluid, MRI scans and cognitive testing obtained from cognitively normal individuals can be used to predict likelihood of progression to mild cognitive impairment several years later, for groups of individuals. However, it remains unclear whether these measures are useful for predicting likelihood of progression for an individual. The increasing focus on early intervention in clinical trials for Alzheimer's disease emphasizes the importance of improving the ability to identify which cognitively normal individuals are more likely to progress over time, thus allowing researchers to efficiently screen participants, as well as determine the efficacy of any treatment intervention. The goal of this study was to determine which measures, o

SUBMITTER: Albert M 

PROVIDER: S-EPMC5837651 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature