Stent and leaflet stresses in a 26-mm first-generation balloon-expandable transcatheter aortic valve.

ABSTRACT:

Objective

Transcatheter aortic valve replacement is established therapy for high-risk and inoperable patients with severe aortic stenosis, but questions remain regarding long-term durability. Valve design influences durability. Increased leaflet stresses in surgical bioprostheses have been correlated with degeneration; however, transcatheter valve leaflet stresses are unknown. From 2007 to 2014, a majority of US patients received first-generation balloon-expandable transcatheter valves. Our goal was to determine stent and leaflet stresses in this valve design using finite element analyses.

Methods

A 26-mm Sapien Transcatheter Heart Valve (Edwards Lifesciences, Inc, Irvine, Calif) underwent high-resolution microcomputed tomography scanning to develop precise 3-dimensional geo

SUBMITTER: Xuan Y 

PROVIDER: S-EPMC5837867 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature