Plasma concentrations of lipids during pregnancy and the risk of gestational diabetes mellitus: A longitudinal study.

ABSTRACT:

Background

Abnormal lipid profiles have been associated with gestational diabetes mellitus (GDM), but studies with longitudinal measures of lipids throughout pregnancy are sparse. The aim of the present study was to characterize longitudinal changes in lipid profiles throughout pregnancy and prospectively examine the associations of plasma lipid concentrations with risk of GDM.

Methods

This study was a nested case-control study including 107 GDM cases and 214 matched non-GDM controls from participants in the National Institute of Child Health and Human Development (NICHD) Fetal Growth Studies - Singleton cohort. Blood samples were collected longitudinally at Gestational Weeks (GW) 10-14, 15-26 (fasting sample), 23-31, and 33-39. Plasma concentrations of triglycerides, total

SUBMITTER: Bao W 

PROVIDER: S-EPMC5837900 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature