Sea urchin histamine receptor 1 regulates programmed cell death in larval Strongylocentrotus purpuratus.

ABSTRACT: Settlement is a rapid process in many marine invertebrate species, transitioning a planktonic larva into a benthic juvenile. In indirectly developing sea urchins, this ecological transition correlates with a morphological, developmental and physiological transition (metamorphosis) during which apoptosis is essential for the resorption and remodelling of larval and juvenile structures. While settlement is initiated by environmental cues (i.e. habitat-specific or benthic substrate cues), metamorphosis is regulated by developmental endocrine signals, such as histamine (HA), thyroid hormones (THs) and nitric oxide (NO). In the purple sea urchin, Strongylocentrotus purpuratus, we found that suH1R mRNA levels increase during larval development and peak during metamorphic competence. SuH1R positi

SUBMITTER: Lutek K 

PROVIDER: S-EPMC5838261 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature