Whole-genome association and genome partitioning revealed variants and explained heritability for total number of teats in a Yorkshire pig population.

ABSTRACT: OBJECTIVE:The study was designed to perform a genome-wide association (GWA) and partitioning of genome using Illumina's PorcineSNP60 Beadchip in order to identify variants and determine the explained heritability for the total number of teats in Yorkshire pig. METHODS:After screening with the following criteria: minor allele frequency, MAF≤0.01; Hardy-Weinberg equilibrium, HWE≤0.000001, a pair-wise genomic relationship matrix was produced using 42,953 single nucleotide polymorphisms (SNPs). A genome-wide mixed linear model-based association analysis (MLMA) was conducted. And for estimating the explained heritability with genome- or chromosome-wide SNPs the genetic relatedness estimation through maximum likelihood approach was used in our study. RESULTS:The MLMA analysis and false discovery

SUBMITTER: Uzzaman MR 

PROVIDER: S-EPMC5838318 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature