An algorithmic approach for the treatment of severe uncontrolled asthma.

ABSTRACT: A small subgroup of patients with asthma suffers from severe disease that is either partially controlled or uncontrolled despite intensive, guideline-based treatment. These patients have significantly impaired quality of life and although they constitute <5% of all asthma patients, they are responsible for more than half of asthma-related healthcare costs. Here, we review a definition for severe asthma and present all therapeutic options currently available for these severe asthma patients. Moreover, we suggest a specific algorithmic treatment approach for the management of severe, difficult-to-treat asthma based on specific phenotype characteristics and biomarkers. The diagnosis and management of severe asthma requires specialised experience, time and effort to comprehend the needs and ex

SUBMITTER: Zervas E 

PROVIDER: S-EPMC5838355 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature