Apathy in rapid eye movement sleep behaviour disorder is common and under-recognized.

ABSTRACT:

Background and purpose

Apathy is an important neuropsychiatric feature of Parkinson's disease (PD), which often emerges before the onset of motor symptoms. Patients with rapid eye movement sleep behaviour disorder (RBD) have a high probability of developing PD in future. Neuropsychiatric problems are common in RBD, but apathy has not previously been detailed in this key prodromal population.

Methods

Eighty-eight patients with polysomnographically proven RBD, 65 patients with PD and 33 controls were assessed for apathy using the Lille Apathy Rating Scale. Cognition and depression were also quantified. The sensitivity of the Unified Parkinson's Disease Rating Scale screening questions for apathy and depression was calculated.

Results

A total of 46% of patients with RBD

SUBMITTER: Barber TR 

PROVIDER: S-EPMC5838543 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature