Bilateral Deep Brain Stimulation of the Nucleus Basalis of Meynert for Parkinson Disease Dementia: A Randomized Clinical Trial.

ABSTRACT:

Importance

Deep brain stimulation of the nucleus basalis of Meynert (NBM DBS) has been proposed as a treatment option for Parkinson disease dementia.

Objective

To evaluate the safety and potential symptomatic effects of NBM DBS in patients with Parkinson disease dementia.

Design, setting, and participants

A randomized, double-blind, crossover clinical trial evaluated the results of 6 patients with Parkinson disease dementia who were treated with NBM DBS at a neurosurgical referral center in the United Kingdom from October 26, 2012, to July 31, 2015. Eligible patients met the diagnostic criteria for Parkinson disease dementia, had motor fluctuations, were appropriate surgical candidates aside from the coexistence of dementia, were age 35 to 80 years, were able to give

SUBMITTER: Gratwicke J 

PROVIDER: S-EPMC5838617 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature