Early life Triclosan exposure and child adiposity at 8 Years of age: a prospective cohort study.

ABSTRACT:

Background

Triclosan is an antimicrobial agent that may affect the gut microbiome and endocrine system to influence adiposity. However, little data from prospective studies examining prenatal and childhood exposures exist. We investigated the relationship between multiple, prospective early life measure of triclosan exposure and child adiposity.  METHODS: In a prospective cohort of 220 mother-child pairs from Cincinnati, OH (enrolled 2003-2006), we quantified triclosan in urine samples collected twice during pregnancy, annually from 1 to 5 years of age, and once at 8 years. We assessed child adiposity at age 8 years using body mass index (BMI), waist circumference, and bioelectric impedance. We estimated covariate-adjusted associations of child adiposity with a 10-fold increase in

SUBMITTER: Kalloo G 

PROVIDER: S-EPMC5838861 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature