Pigmentary mosaicism: a review of original literature and recommendations for future handling.

ABSTRACT: BACKGROUND:Pigmentary mosaicism is a term that describes varied patterns of pigmentation in the skin caused by genetic heterogeneity of the skin cells. In a substantial number of cases, pigmentary mosaicism is observed alongside extracutaneous abnormalities typically involving the central nervous system and the musculoskeletal system. We have compiled information on previous cases of pigmentary mosaicism aiming to optimize the handling of patients with this condition. Our study is based on a database search in PubMed containing papers written in English, published between January 1985 and April 2017. The search yielded 174 relevant and original articles, detailing a total number of 651 patients. RESULTS:Forty-three percent of the patients exhibited hyperpigmentation, 50% exhibited hypopigm

SUBMITTER: Kromann AB 

PROVIDER: S-EPMC5839061 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature