Association of Preoperatively Diagnosed Patent Foramen Ovale With Perioperative Ischemic Stroke.

ABSTRACT:

Importance

Perioperative stroke is a major complication for patients undergoing surgery. Patent foramen ovale (PFO) represents a possible anatomical link between venous thrombosis and stroke.

Objective

To determine whether a preoperatively diagnosed PFO is associated with increased risk of perioperative ischemic stroke.

Design, setting, and participants

Retrospective cohort study from Massachusetts General Hospital and 2 affiliated community hospitals between January 1, 2007, and December 31, 2015. Participants were 182 393 consecutive adults undergoing noncardiac surgery with general anesthesia.

Exposures

Preoperatively diagnosed PFO.

Main outcomes and measures

Perioperative ischemic stroke occurring within 30 days of surgery; stroke subtype by Oxfordsh

SUBMITTER: Ng PY 

PROVIDER: S-EPMC5839297 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature