Association of Intracerebral Hemorrhage Among Patients Taking Non-Vitamin K Antagonist vs Vitamin K Antagonist Oral Anticoagulants With In-Hospital Mortality.

ABSTRACT:

Importance

Although non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly used to prevent thromboembolic disease, there are limited data on NOAC-related intracerebral hemorrhage (ICH).

Objective

To assess the association between preceding oral anticoagulant use (warfarin, NOACs, and no oral anticoagulants [OACs]) and in-hospital mortality among patients with ICH.

Design, setting, and participants

Retrospective cohort study of 141 311 patients with ICH admitted from October 2013 to December 2016 to 1662 Get With The Guidelines-Stroke hospitals.

Exposures

Anticoagulation therapy before ICH, defined as any use of OACs within 7 days prior to hospital arrival.

Main outcomes and measures

In-hospital mortality.

Results

Among 141 311 patie

SUBMITTER: Inohara T 

PROVIDER: S-EPMC5839299 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature