Age Effect on Automatic Inhibitory Function of the Somatosensory and Motor Cortex: An MEG Study.

ABSTRACT: Age-related deficiency in the top-down modulation of cognitive inhibition has been extensively documented, whereas the effects of age on a bottom-up or automatic operation of inhibitory function were less investigated. It is unknown that whether the older adults (OA)' reduced behavioral performance and neural responses are due to the insufficient bottom-up processes. Compared to behavioral assessments which have been widely used to examine the top-down control of response inhibition, electrophysiological recordings are more suitable to probe the early-stage processes of automatic inhibitory function. Sensory gating (SG), a phenomenon of attenuated neural response to the second identical stimulus in a paired-pulse paradigm, is an indicator to assess automatic inhibitory function of the sens

SUBMITTER: Cheng CH 

PROVIDER: S-EPMC5840154 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature