Long-term study of the association of adipokines and glucose variability with diabetic complications.

ABSTRACT:

Background/aims

Recent studies have suggested an important role of adipokines in the development of insulin resistance and diabetes mellitus. The clinical relevance of adipokines on long-term outcomes in patients with diabetes and chronic kidney disease is uncertain. The purpose of this study was to identify a predictable factor in patients with long-term diabetic complications.

Methods

A total of 161 diabetic individuals were followed-up from 2002 to 2013. Circulating plasma levels of adiponectin, glypican-4, irisin, visfatin, and visit-to-visit glucose variability were measured in diabetic patients. Associations among adipokines and variable metabolic parameters and microvascular, and macrovascular complications were evaluated.

Results

Plasma adiponectin and glypica

SUBMITTER: Cha JJ 

PROVIDER: S-EPMC5840591 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature