Chronic non-freezing cold injury results in neuropathic pain due to a sensory neuropathy.

ABSTRACT: Non-freezing cold injury develops after sustained exposure to cold temperatures, resulting in tissue cooling but not freezing. This can result in persistent sensory disturbance of the hands and feet including numbness, paraesthesia and chronic pain. Both vascular and neurological aetiologies of this pain have been suggested but remain unproven. We prospectively approached patients referred for clinical assessment of chronic pain following non-freezing cold injury between 12 February 2014 and 30 November 2016. Of 47 patients approached, 42 consented to undergo detailed neurological evaluations including: questionnaires to detail pain location and characteristics, structured neurological examination, quantitative sensory testing, nerve conduction studies and skin biopsy for intraepidermal ne

SUBMITTER: Vale TA 

PROVIDER: S-EPMC5841153 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature