Contrasting mortality risks among subgroups of treated hypertensive patients developing new-onset diabetes.

ABSTRACT:

Aims

Hypertension and diabetes mellitus (DM) frequently cluster together and synergistically increase cardiovascular risk. Among those who develop DM during treatment for hypertension (new-onset diabetes, NOD), it is unclear whether NOD reflects a separate entity associated with increased risk or merely reflects accelerated presentation of DM.

Methods and results

We analysed data on 15 089 hypertensive patients attending the Glasgow Blood Pressure Clinic. The date at first hospital encounter either with diagnosis of diabetes or prescription of anti-hyperglycaemic medication were considered as the onset of diabetes. Cox proportional hazard models (including propensity score matching) were employed to study associations between diabetes status, early and late NOD (diagnosis <1

SUBMITTER: Lip S 

PROVIDER: S-EPMC5841224 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature