Material properties of the brain in injury-relevant conditions - Experiments and computational modeling.

ABSTRACT: Material properties of the brain have been extensively studied but remain poorly characterized. The vast variations in constitutive models and material constants are well documented. However, no study exists to translate the variations into disparities in impact-induced brain strains most relevant to brain injury. Here, we reviewed a subset of injury-relevant brain material properties either characterized in experiments or adopted in recent head injury models. To highlight how variations in measured brain material properties manifested in simulated brain strains, we selected six experiments that have provided a complete set of brain material model and constants to implement a common head injury model. Responses resulting from two extreme events representing a high-rate cadaveric head impac

SUBMITTER: Zhao W 

PROVIDER: S-EPMC5841256 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature