Neurodevelopmental problems at 18 months among children exposed to paracetamol in utero: a propensity score matched cohort study.

ABSTRACT:

Background

Previous studies showed that children exposed to paracetamol during fetal life might have an increased risk of neurodevelopmental problems. Since paracetamol is one of the most commonly used medications during pregnancy, even small increases in the risk of neurodevelopmental problems may have considerable implications for public health.

Methods

Using data from the Norwegian Mother and Child Cohort Study, we applied propensity score (PS) matching to examine associations between prenatal paracetamol exposure and neurodevelopmental problems among children at 18 months of age. Paracetamol use was classified into short-term (< 28 days) and long-term (≥ 28 days) of exposure.

Results

Of the 51 200 pregnancies included in our study, 40.5% of mothers ( n  = 20 749)

SUBMITTER: Vlenterie R 

PROVIDER: S-EPMC5841617 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature