Survival in Southern European patients waitlisted for kidney transplant after graft failure: A competing risk analysis.

ABSTRACT:

Background

Whether patients waitlisted for a second transplant after failure of a previous kidney graft have higher mortality than transplant-näive waitlisted patients is uncertain.

Methods

We assessed the relationship between a failed transplant and mortality in 3851 adult KT candidates, listed between 1984-2012, using a competing risk analysis in the total population and in a propensity score-matched cohort. Mortality was also modeled by inverse probability weighting (IPTW) competing risk regression.

Results

At waitlist entry 225 (5.8%) patients had experienced transplant failure. All-cause mortality was higher in the post-graft failure group (16% vs. 11%; P = 0.033). Most deaths occurred within three years after listing. Cardiovascular disease was the leading cause

SUBMITTER: Hernandez D 

PROVIDER: S-EPMC5841738 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature