A new perspective on the pathogenesis of chronic renal disease in captive cheetahs (Acinonyx jubatus).

ABSTRACT: The sustainability of captive cheetah populations is limited by high mortality due to chronic renal disease. This necropsy study, conducted on 243 captive cheetahs from one institution, investigated the relationships between focal palatine erosions, gastritis, enterocolitis, glomerulosclerosis, chronic renal infarcts, renal cortical and medullary fibrosis, and renal medullary amyloidosis at death. Associations between the individual renal lesions and death due to chronic renal disease and comparisons of lesion prevalence between captive bred and wild born and between normal and king coated cheetahs were also assessed. All lesions were significantly positively correlated with age at death. Renal medullary fibrosis was the only lesion associated with the likelihood of death being due to chro

SUBMITTER: Mitchell EP 

PROVIDER: S-EPMC5841817 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature