Antihypertensive drugs use and the risk of prostate cancer: a meta-analysis of 21 observational studies.

ABSTRACT:

Background

Due to the lack of strong evidence to identify the relationship between antihypertensive drugs use and the risk of prostate cancer, it was needed to do a systematic review to go into the subject.

Methods

We systematically searched PubMed, Web of Science and Embase to identify studies published, through May 2015. Two evaluators independently reviewed and selected articles involving the subject. We used the Newcastle-Ottawa Scale (NOS) to assess the quality of the studies. All extracted results to evaluate the relationship between antihypertensive drugs usage and prostate cancer risk were pool-analysed using Stata 12.0 software.

Results

A total of 12 cohort and 9 case-control studies were ultimately included in our review. Most of the studies were evaluated t

SUBMITTER: Cao L 

PROVIDER: S-EPMC5842557 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature