Task-free spectral EEG dynamics track and predict patient recovery from severe acquired brain injury.

ABSTRACT: For some patients, coma is followed by a state of unresponsiveness, while other patients develop signs of awareness. In practice, detecting signs of awareness may be hindered by possible impairments in the patient's motoric, sensory, or cognitive abilities, resulting in a substantial proportion of misdiagnosed disorders of consciousness. Task-free paradigms that are independent of the patient's sensorimotor and neurocognitive abilities may offer a solution to this challenge. A limitation of previous research is that the large majority of studies on the pathophysiological processes underlying disorders of consciousness have been conducted using cross-sectional designs. Here, we present a study in which we acquired a total of 74 longitudinal task-free EEG measurements from 16 patients (aged

SUBMITTER: van den Brink RL 

PROVIDER: S-EPMC5842643 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature