Brain functional connectivity in sleep-related hypermotor epilepsy.

ABSTRACT:

Objectives

To evaluate functional connectivity (FC) in patients with sleep-related hypermotor epilepsy (SHE) compared to healthy controls.

Methods

Resting state fMRI was performed in 13 patients with a clinical diagnosis of SHE (age = 38.3 ± 11.8 years, 6 M) and 13 matched healthy controls (age = 38.5 ± 10.8 years, 6 M).Data were first analysed using probabilistic independent component analysis (ICA), then a graph theoretical approach was applied to assess topological and organizational properties at the whole brain level. We evaluated node degree (ND), betweenness centrality (BC), clustering coefficient (CC), local efficiency (LE) and global efficiency (GE). The differences between the two groups were evaluated non-parametrically.

Results

At the group level, we disti

SUBMITTER: Evangelisti S 

PROVIDER: S-EPMC5842749 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature