Callous-unemotional traits and brain structure: Sex-specific effects in anterior insula of typically-developing youths.

ABSTRACT: Callous-unemotional traits are characterized by a lack of empathy, a disregard for others' feelings and shallow or deficient affect, such as a lack of remorse or guilt. Neuroanatomical correlates of callous-unemotional traits have been demonstrated in clinical samples (i.e., adolescents with disruptive behavior disorders). However, it is unknown whether callous-unemotional traits are associated with neuroanatomical correlates within normative populations without clinical levels of aggression or antisocial behavior. Here we investigated the relationship between callous-unemotional traits and gray matter volume using voxel-based morphometry in a large sample of typically-developing boys and girls (N = 189). Whole-brain multiple regression analyses controlling for site, total intracran

SUBMITTER: Raschle NM 

PROVIDER: S-EPMC5842751 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature