Development of a quantitative intracranial vascular features extraction tool on 3D MRA using semiautomated open-curve active contour vessel tracing.

ABSTRACT:

Purpose

To develop a quantitative intracranial artery measurement technique to extract comprehensive artery features from time-of-flight MR angiography (MRA).

Methods

By semiautomatically tracing arteries based on an open-curve active contour model in a graphical user interface, 12 basic morphometric features and 16 basic intensity features for each artery were identified. Arteries were then classified as one of 24 types using prediction from a probability model. Based on the anatomical structures, features were integrated within 34 vascular groups for regional features of vascular trees. Eight 3D MRA acquisitions with intracranial atherosclerosis were assessed to validate this technique.

Results

Arterial tracings were validated by an experienced neuroradiologist who

SUBMITTER: Chen L 

PROVIDER: S-EPMC5843519 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature