Cardiovascular disease in a nationwide population of Danish women with polycystic ovary syndrome.

ABSTRACT: BACKGROUND:Polycystic ovary syndrome (PCOS) is associated with obesity and low grade inflammation and the risk for cardiovascular disease (CVD) could be increased in PCOS. METHODS:National register-based study including women with PCOS and no previous diagnosis of CVD, hypertension, or dyslipidemia. PCOS Denmark (N = 18,112) included women with PCOS in the Danish National Patient Register. PCOS Odense University Hospital (OUH, N = 1165) was an embedded cohort including premenopausal women with PCOS and clinical and biochemical examination. Three age-matched controls were included per patient in PCOS Denmark (N = 52,769). The main study outcome was CVD events including hypertension and dyslipidemia defined according to nationwide in- and outpatient hospital contact diagnosis codes and/or in

SUBMITTER: Glintborg D 

PROVIDER: S-EPMC5844097 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature