Impacts of age and sex on retinal layer thicknesses measured by spectral domain optical coherence tomography with Spectralis.

ABSTRACT:

Objective

To examine differences in individual retinal layer thicknesses measured by spectral domain optical coherence tomography (SD-OCT) (Spectralis®) produced with age and according to sex.

Design

Cross-sectional, observational study.

Methods

The study was conducted in 297 eyes of 297 healthy subjects aged 18 to 87 years. In one randomly selected eye of each participant the volume and mean thicknesses of the different macular layers were measured by SD-OCT using the instrument's macular segmentation software.

Main outcome measures

Volume and mean thickness of macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), retinal pigmentary e

SUBMITTER: Nieves-Moreno M 

PROVIDER: S-EPMC5844598 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature