Significant association between interleukin-10 gene polymorphisms and cervical cancer risk: a meta-analysis.

ABSTRACT: Previous studies have suggested that interleukin-10 (IL-10) polymorphisms may be associated with an increased risk of developing cervical cancer. However, the published results on this subject matter are controversial. The aim of this study was to conduct a meta-analysis of published reports to more precisely investigate the relationship between IL-10 polymorphisms and cervical cancer risk. Five online databases (PubMed, Embase, Web of SCI, CNKI and Wanfang) were searched, and seventeen articles with sufficient quantitative information were included in our meta-analysis. The odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to assess the association between IL-10 polymorphisms and cervical cancer risk. Publication bias, sensitivity and cumulative analyses were also perfo

SUBMITTER: Guo C 

PROVIDER: S-EPMC5844753 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature