Investigation of 12 X-STR loci in Mongolian and Eastern Han populations of China with comparison to other populations.

ABSTRACT: Due to the unique inheritance pattern, X-chromosomal short tandem repeats (X-STRs) have several advantages in complex kinship cases, such as deficiency cases or grandparent-grandchild and half-sisters testing. In our study, 541 unrelated individuals gathered from Mongolian and Eastern Chinese Han populations were successfully genotyped using the Investigator Argus X-12 kit. We calculated allele/haplotype frequencies and other forensic parameters of the two populations and further explored their genetic distance with already published Chinese populations and six global populations. Our results showed that the 12 X-STR markers were highly informative in the two populations when compared with nine other Chinese populations: significant differences were found at several loci. Geographically ne

SUBMITTER: Tao R 

PROVIDER: S-EPMC5844901 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature