Quasi-periodic patterns of intrinsic brain activity in individuals and their relationship to global signal.

ABSTRACT: Quasiperiodic patterns (QPPs) as reported by Majeed et al., 2011 are prominent features of the brain's intrinsic activity that involve important large-scale networks (default mode, DMN; task positive, TPN) and are likely to be major contributors to widely used measures of functional connectivity. We examined the variability of these patterns in 470 individuals from the Human Connectome Project resting state functional MRI dataset. The QPPs from individuals can be coarsely categorized into two types: one where strong anti-correlation between the DMN and TPN is present, and another where most areas are strongly correlated. QPP type could be predicted by an individual's global signal, with lower global signal corresponding to QPPs with strong anti-correlation. After regression of global signa

SUBMITTER: Yousefi B 

PROVIDER: S-EPMC5845807 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature