An Advanced Multifunctional Hydrogel-Based Dressing for Wound Monitoring and Drug Delivery.

ABSTRACT: Wound management is a major global challenge and poses a significant financial burden to the healthcare system due to the rapid growth of chronic diseases such as diabetes, obesity, and aging population. The ability to detect pathogenic infections and release drug at the wound site is of the utmost importance to expedient patient care. Herein, this study presents an advanced multifunctional dressing (GelDerm) capable of colorimetric measurement of pH, an indicator of bacterial infection, and release of antibiotic agents at the wound site. This study demonstrates the ability of GelDerm to detect bacterial infections using in vitro and ex vivo tests with accuracies comparable to the commercially available systems. Wireless interfaces to digital image capture hardware such as smartphones serv

SUBMITTER: Mirani B 

PROVIDER: S-EPMC5845857 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature