Geriatric assessment may help decision-making in elderly patients with inoperable, locally advanced non-small-cell lung cancer.

ABSTRACT:

Background

Although concurrent chemoradiotherapy (cCRT) increases survival in patients with inoperable, locally advanced non-small-cell lung cancer (NSCLC), there is no consensus on the treatment of elderly patients. The aim of this study was to determine the prognostic value of the comprehensive geriatric assessment (CGA) and its ability to predict toxicity in this setting.

Methods

We enrolled 85 consecutive elderly (⩾75 years) participants, who underwent CGA and the Vulnerable Elders Survey (VES-13). Those classified as fit and medium-fit by CGA were deemed candidates for cCRT (platinum-based chemotherapy concurrent with thoracic radiation therapy), while unfit patients received best supportive care.

Results

Fit (37%) and medium-fit (48%) patients had significantly

SUBMITTER: Antonio M 

PROVIDER: S-EPMC5846066 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature