Perioperative Ketamine for Analgesia in Spine Surgery: A Meta-analysis of Randomized Controlled Trials.

ABSTRACT:

Study design

A meta-analysis of randomized controlled trials (RCTs).

Objective

The aim of this study was to evaluate the effectiveness of perioperative supplemental ketamine to reduce postoperative opioid analgesic consumption following spine surgery.

Summary of background data

Although low-dose supplemental ketamine has been known to reduce pain after surgery, there is conflicting evidence regarding whether ketamine can be effective to reduce opioid consumption following spine surgery.

Methods

Comprehensive search of PubMed, the Cochrane Central Register of Controlled Trials for prospective RCTs, Web of Science, and Scopus. Patients who received supplemental ketamine were compared with the control group in terms of postoperative morphine equivalent consumption

SUBMITTER: Pendi A 

PROVIDER: S-EPMC5846492 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature