Improved urethral fluorescence during low rectal surgery: a new dye and a new method.

ABSTRACT:

Background

The aim of this study was to demonstrate highlighting of the urethra during surgery through the use of two different methods: a new near-infrared fluorophore IRDye800BK, and indocyanine green (ICG) mixed with silicone.

Methods

Male cadavers from the department of anatomy at the University of Oxford were used to visualise the urethra during near-infrared fluorescence excitation. To assess IRDye800BK, a perineal incision was utilised after infiltrating the urethra directly with an IRDye800BK solution mixed with Instillagel. ICG-silicone was assessed when the urethra was purposely exposed as part of a simulated transanal total mesorectal dissection. ICG was previously mixed with ethanol and silicone and left to set in a Foley catheter. Fluorescence was visualised usi

SUBMITTER: Barnes TG 

PROVIDER: S-EPMC5846816 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature