A high working memory load prior to memory retrieval reduces craving in non-treatment seeking problem drinkers.

ABSTRACT: BACKGROUND:Reconsolidation-based interventions have been suggested to be a promising treatment strategy for substance use disorders. In this study, we aimed to investigate the effectiveness of a working memory intervention to interfere with the reconsolidation of alcohol-related memories in a sample of non-treatment seeking heavy drinkers. METHODS:Participants were randomized to one of the two conditions that underwent a 3-day intervention: in the experimental condition, a 30-min working memory training was performed immediately after a 15-min memory retrieval session (i.e., within the memory reconsolidation time-window), whereas in the control condition, the working memory training was performed prior to a memory retrieval session. RESULTS:In contrast to our original hypothesis, a high wo

SUBMITTER: Kaag AM 

PROVIDER: S-EPMC5847068 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature