Echocardiographic Measures and Estimated GFR Decline Among African Americans: The Jackson Heart Study.

ABSTRACT:

Background

Cardiac structural abnormalities, common in African Americans, are associated with adverse clinical outcomes. Associations between echocardiography-measured subclinical heart failure and kidney function decline are unknown and may identify novel risk factors for kidney disease in this population.

Study design

Prospective cohort study.

Setting & participants

2,418 Jackson Heart Study participants with baseline echocardiograms and longitudinal measures of estimated glomerular filtration rate (eGFR) calculated from the CKD-EPI creatinine equation. 2,219 participants had baseline eGFRs≥60mL/min/1.73m².

Predictors

Left ventricular mass (LVM) and ejection fraction (LVEF) and pulmonary artery systolic pressure (PASP) quantified from baseline echo

SUBMITTER: Zelnick LR 

PROVIDER: S-EPMC5848095 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature