Relationship Between Physical Activity, Body Mass Index, and Risk of Heart Failure.

ABSTRACT:

Background

Lower leisure-time physical activity (LTPA) and higher body mass index (BMI) are independently associated with risk of heart failure (HF). However, it is unclear if this relationship is consistent for both heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF).

Objectives

This study sought to quantify dose-response associations between LTPA, BMI, and the risk of different HF subtypes.

Methods

Individual-level data from 3 cohort studies (WHI [Women's Health Initiative], MESA [Multi-Ethnic Study of Atherosclerosis], and CHS [Cardiovascular Health Study]) were pooled and participants were stratified into guideline-recommended categories of LTPA and BMI. Associations between LTPA, BMI, and risk of overall

SUBMITTER: Pandey A 

PROVIDER: S-EPMC5848099 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature