Correlation between measles vaccine doses: implications for the maintenance of elimination.

ABSTRACT: Measles eradication efforts have been successful at achieving elimination in many countries worldwide. Such countries actively work to maintain this elimination by continuing to improve coverage of two routine doses of measles vaccine following measles elimination. While improving measles vaccine coverage is always beneficial, we show, using a steady-state analysis of a dynamical model, that the correlation between populations receiving the first and second routine dose also has a significant impact on the population immunity achieved by a specified combination of first and second dose coverage. If the second dose is administered to people independently of whether they had the first dose, high second-dose coverage improves the proportion of the population receiving at least one dose, and w

SUBMITTER: McKee A 

PROVIDER: S-EPMC5848754 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature